Announcing our investment in Minneapolis-based OneDose®, a software that helps paramedics and emergency medical professionals make faster, more accurate treatment decisions.
The EMS industry is rapidly shifting away from paper protocols and manual processes, yet critical decisions in the first mile of care are still often made without reliable digital tools. OneDose® is built to address that gap. The company is targeting EMS departments and hospital emergency departments to reimagine the source of truth from dispatch to handoff. Their vision is to become the “Microsoft for EMS” by consolidating fragmented workflows into a single AI-powered platform that supports clinical decision making and captures patient data across the entire care continuum.
OneDose approaches this challenge through two integrated products. OneDose® is the company’s software platform that standardizes bedside protocols and captures real-time clinical data, helping paramedics make consistent treatment decisions under pressure. Complementing the software is OneWeight®, stretcher-integrated hardware that provides precise patient weight measurements, replacing inaccurate estimation methods like the Broselow tape that are still widely used today. Together, the hardware and software create a tightly integrated workflow that improves dosing accuracy and clinical documentation during high-stress emergency scenarios.
The founding team gives us exceptional confidence in their ability to execute. The three technical co-founders bring complementary engineering backgrounds and have developed deep domain expertise quickly; they've scaled the business to reach more than 3000 EMS agencies across 40 states. Their hardware-software integration creates a strong competitive moat that pure software competitors cannot easily replicate, a dynamic already reflected in competitive wins such as replacing legacy solutions across an entire regional EMS network in Western Arizona. Across reference calls and industry conversations, we repeatedly heard the same feedback: the team executes far beyond expectations for founders at this stage and consistently incorporates feedback from advisors and customers.
“What started as a hardware solution for patient weighing revealed a much bigger problem: the first mile of care is still largely analog,” said Abhinaya Konduru, Partner. “OneDose is tackling that head on, giving paramedics real-time decision support in the moments that matter most. We backed this team because they started close to the problem and have the technical depth and ambition to build the system of record for pre-hospital care.”
With this investment, OneDose plans to accelerate development of its EMS AI assistant, including voice-enabled workflows and real-time quality management features that can support larger enterprise customers such as major metropolitan fire departments. Just as important, the founders have built an impressive network of industry veterans and experienced operators around them. That combination of coachability, technical depth, and strong early traction gives us confidence in their ability to scale within a complex, highly regulated healthcare environment.
We’re excited to partner with OneDose as they work to modernize emergency medical workflows and capture a meaningful share of the growing opportunity to digitize pre-hospital care.
About OneDose: OneDose® is an AI-driven EMS platform that seamlessly connects clinical point-of-care solutions—from pre-scene to hospital handoff. By unifying protocols, dosing support, documentation, and real-time clinical tools into a single workflow, OneDose empowers emergency clinicians to deliver faster, safer, and more accurate care, even in the most unpredictable conditions. For more information, please visit www.myonedose.com.
Learn more: OneDose® Secures Funding to Enhance Emergency Care Platform
About M25: M25 is an early-stage software-focused venture firm based in Chicago, investing solely in tech startups headquartered in the Midwest. Since launching in 2015, M25 has become the most active investor in the region, quickly becoming the preferred seed investor for the next generation of Midwest unicorns. Portfolio companies include Kin Insurance, Loop Returns, Astronomer, Branch Pay, Authenticx and more. For more information, please visit www.m25vc.com.
